Actitrexx GmbH is a new biotech start-up and was founded in 2020. Our vision is to offer a curative cellular therapy to prevent inflammatory reactions in conditions like GVHD, solid organ transplantation, and autoimmune diseases. Regulatory T cells (TREG) - natural guardian cells of the immune system - are the key players of our cell-based drug product. Isolated TREG are activated ex vivo via specific methods and administered to patients intravenously. Unlike other comparable approaches, activated TREG (ATREG) will not be expanded in vitro, protecting them against a possible loss of function. Thus, ATREG is a safe and efficient treatment option for transplanted patients, preventing and providing substantial decrease of GVHD severity and related mortality as well. The founders of Actitrexx GmbH combine many years of unique experience in basic research, biotechnology, clinical application, and pharmaceutical development. The management team is supported and complemented by a strong network.

Rhineland-Palatinate, Germany

Mainz, Germany

Actitrexx GMBH

The seed investor High-Tech Gründerfonds (HTGF) finances tech start-ups with growth potential and has supported more than 700 start-ups since 2005. With the launch of its fourth fund, HTGF now has about 1.4 billion euros under management. Its team of experienced investment managers and start-up experts support young companies with expertise, entrepreneurial spirit and passion. HTGF’s focus is on high-tech start-ups in the fields of digital tech, industrial tech, life sciences, chemistry and related business areas. To date, external investors have injected about 5 billion euros of capital into the HTGF portfolio via more than 2,000 follow-on financing rounds. In addition, HTGF has already successfully sold shares in more than 170 companies. Fund investors in this public-private partnership include the German Federal Ministry for Economic Affairs and Climate Action, KfW Capital and 45 companies from a wide range of industries. Fund investors in this public-private partnership include the German Federal Ministry for Economic Affairs and Climate Action, KfW Capital and 45 companies from a wide range of industries.

High-Tech Gründerfonds Management GmbH

HTGF 

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Signal that you'd be interested in working with a HTGF company to help us put the right opportunities at great companies on your radar. The choice to pursue a new career move is then up to you.

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Browse through our portfolio jobs and select a suitable opportunity.Our HTGF Portfolio of startups offers excellent opportunities and is always hiring talented people.

Browse through our portfolio jobs and select a suitable opportunity.
Our HTGF Portfolio of startups offers excellent opportunities and is always hiring talented people.